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Genome Editing Tools and directed integration for the future of Bioscience and Medicine

Abbie – A Binding Based Integrase Edito,Patent Granted in CN,Patent Pending in JP, KR, EP and US.

Advantages:

  • Does not completely reply on endogenous host mechanisms of repair for integration
  • Does not induce double – stranded DNA breals
  • Is effective in non-dividing cells
  • Potential to drastically increase the “Payload” size of exogenous DNA to be delivered and allow for more sophisticated “gene circuits” to be easily introduced
  • Decreased time to result thereby loweing experimental and cell therapy manufacturing costs
  • Unique IP with the potential to expand portfolio in the gene editing space.
    Saves – TIME – MONEY 

ABBIE Integration Kit

  • Easy integration to AAVS1 safe harbor location
  • Over 10Kb inserts tested
  • Same day results (6h hour depending on cell type)
  • Custom Donor Design Assistance
  • Fast work flow (1 hour)
  • 30 Reactions reactions
  • Optimized for human gene editing
  • Currently optimized for HEK & T-Cell targeting.
  • Additional cell lines in the pipeline
  • Kit contains eGFP donor DNA
  • Positive control sgRNA designed for human AAVS1
  • ABBIE mRNA or Protein
  • Buffers for lipid-based transfection
    This product is intended for research use only and is not intended for human or animal use.Store at 4C